Pharmacological action and mechanisms of ginkgolide B
نویسندگان
چکیده
منابع مشابه
Intracellular Signaling Mechanisms Pharmacological Action of Jasminum amplexicaule Buch.-Ham. (Oleaceae) on Gastrointestinal Secretion
Jasminum amplexicaule Buch.-Ham. (Oleaceae) has been commonly used in the traditional medicine in dysentery, diarrhoea and bellyache in China. In the present work, the methanol extract of Jasminum amplexicaule (JME) was examined for pharmacology on human colonic epithelial cell line T84 by the short-circuit current technique. The results showed that pretreatment of T84 cells with JME produced a...
متن کاملIntracellular Signaling Mechanisms Pharmacological Action of Jasminum amplexicaule Buch.-Ham. (Oleaceae) on Gastrointestinal Secretion
Jasminum amplexicaule Buch.-Ham. (Oleaceae) has been commonly used in the traditional medicine in dysentery, diarrhoea and bellyache in China. In the present work, the methanol extract of Jasminum amplexicaule (JME) was examined for pharmacology on human colonic epithelial cell line T84 by the short-circuit current technique. The results showed that pretreatment of T84 cells with JME produced a...
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Ginkgolide B (GB), an important active constituent of Ginkgo biloba extract, has been used in clinical applications for the treatment of dementia, cerebral insufficiency or related cognitive decline. To investigate the main pharmacokinetic characteristics of three different GB formulations in beagle dogs, a simple, specific and sensitive LC-MS/MS method was established and validated. The separa...
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The terpene trilactones (TTLs), ginkgolides and bilobalide, are structurally unique constituents of Ginkgo biloba extracts, which exhibit various neuromodulatory properties. Although the TTLs are believed to be responsible for some of these effects, the specific interactions with targets in the central nervous system remain to be elucidated on a molecular level. Ginkgolides are known antagonist...
متن کاملintracellular signaling mechanisms pharmacological action of jasminum amplexicaule buch.-ham. (oleaceae) on gastrointestinal secretion
jasminum amplexicaule buch.-ham. (oleaceae) has been commonly used in the traditional medicine in dysentery, diarrhoea and bellyache in china. in the present work, the methanol extract of jasminum amplexicaule (jme) was examined for pharmacology on human colonic epithelial cell line t84 by the short-circuit current technique. the results showed that pretreatment of t84 cells with jme produced a...
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ژورنال
عنوان ژورنال: Chinese Medical Journal
سال: 2007
ISSN: 0366-6999
DOI: 10.1097/00029330-200705020-00013